TB-500 – 5mg

TB-500 (Thymosin Beta-4) is a 43-amino-acid peptide that plays a fundamental role in tissue repair and regeneration. Originally identified in the thymus gland, this protein is now known to be expressed in virtually all cell types — functioning as a key regulator of actin dynamics, cell migration, and wound healing processes.

The peptide’s mechanism centers on its interaction with G-actin, the monomeric form of the cytoskeletal protein actin. By sequestering G-actin, TB-500 promotes cytoskeletal reorganization — enabling cells to change shape, migrate, and respond to tissue damage. This property is particularly important in angiogenesis, where endothelial cells must migrate and proliferate to form new blood vessels.

Preclinical research demonstrates TB-500’s effects across multiple tissue systems. In dermal wound models, it accelerates re-epithelialization by over 40%, enhances collagen deposition, and reduces granulation tissue formation. In cardiac models, it shows cardioprotective effects — preserving cardiac function, reducing infarct volume, and activating endogenous cardiac progenitor cells following ischemic injury. Treated wounds also show superior organized collagen fibers with minimal scarring.

For research teams investigating tissue regeneration, wound healing, cardiac repair, or anti-fibrotic mechanisms, TB-500 provides a well-characterized tool with extensive preclinical literature supporting its biological activity across musculoskeletal, cardiovascular, and soft tissue models.

For research use only. Not for human consumption.